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EPFL, the Swiss Federal Institute of Technology in Lausanne, is one of the most dynamic university campuses in Europe and ranks among the top 20 universities worldwide. The EPFL employs more than 6,500 people supporting the three main missions of the institutions: education, research and innovation. The EPFL campus offers an exceptional working environment at the heart of a community of more than 17,000 people, including over 12,500 students and 4,000 researchers from more than 120 different countries.

Postdoctal Research Position in the field of cancer-immune-engineering

Mission

This project is a collaboration between the laboratory of Prof. Freddy Radtke (Molecula Oncology), at the Swiss Federal Institute of Technology and the Institute of Human Biology (IHB, https://institutehumanbiology.com/), a newly established research center in Basel, Switzerland, dedicated to advancing human biology through the use of human model systems for transitional research.

We offer a postdoctoral research position (100%) to engineer a cancer immunity cycle ex-vivo. The successful candidate will leverage microfabrication and tissue engineering techniques for the ex-vivo integration of lymphatic endothelial cells, dendritic cells, B cells and T cells into a minimal unit of a lymph node (a mini-lymph node) with the goal to bioengineer the initiating arm of the cancer-immunity cycle. This includes antigen capture, antigen presentation and immune cell cross activation within the mini-lymph node.

We expect that this project will enable new experimental tools for the high-resolution dissection of mechanisms governing the cancer-immunity cycle and their translational potential.

Main duties and responsibilities

Driving force in conducting the research, develop the experimental designs and work in collaboration with the immune-engineering team.

 

  • Responsible for experimental design, conducting the experiment, data acquisition and critical evaluation
  • Reporting of research results in lab meetings, seminars, conferences and writing scientific articles.

Profile

The ideal candidate should have:

 

  • PhD degree in immunology
  • Experience in designing and handling immune cells ex-vivo 
  • Experience in multiparameter flow cytometry
  • Experience in tissue culture, cloning techniques and imaging
  • Language skills - good knowledge of English (verbal and writing) a prerequisite
  • Good communication and organizational skills
  • Capacity to collaborate to achieve common objectives
  • Good management and interpersonal skills

We offer

An opportunity to work in cutting-edge projects in a world-renowned scientific community with esteemed scientists, engineers and clinicians. You will work in a dynamic, multidisciplinary, multicultural and collaborative laboratory environment.

EPFL is an international and world-class engineering institution that hosts state-of-the-art experimental and computational facilities, as well as a rich and vibrant scientific and entrepreneurial community.

EPFL is an equal-opportunity employer. We offer competitive salary and benefits, defined by EPFL scales and regulations.

Informations

Contract Start Date : as soon as possible  

Activity Rate : 100 % 

Contract Type: CDD

Duration: 1 year, renewable 

 

Only application through our plateform will be taken into account, at this stage your application shall include:

  • a brief motivation letter (pdf, up to 2 pages)
  • a second pdf that includes -> CV, list of publications, contact details of three referees

 

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