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EPFL, the Swiss Federal Institute of Technology in Lausanne, is one of the most dynamic university campuses in Europe and ranks among the top 20 universities worldwide. The EPFL employs more than 6,500 people supporting the three main missions of the institutions: education, research and innovation. The EPFL campus offers an exceptional working environment at the heart of a community of more than 17,000 people, including over 12,500 students and 4,000 researchers from more than 120 different countries.

Postdoctoral position at EPFL LAPD

Mission

Real time minimally invasive endoscopy for recognition of tumor margins in head and neck cancer using endogenous fluorescence lifetime and machine learning.

Our current research focuses on the identification of tumor margins in head and neck cancers using optical methods, to facilitate the removal of the entire tumor during the first resection surgery and avoiding complications linked to a second resection in case of positive surgical margin.
The technology can be translated to other cancers and we believe the endoscope can be useful for monitoring, and delivering light in deep tissues for photodynamic therapies.

Key technologies developed for this project

  • Fluorescence lifetime imaging (FLIM) of endogenous fluorescence, which we know provides relevant information about the cell's metabolism and allows for a better contrast than solely conventional fluorescence microscopy
  • Machine learning, which allows us to classify normal and tumoral tissues based on their lifetime information
  • Minimally invasive endoscopy, which allows us to probe in deep tissues using a needle-like multimode fiber and reach the >5 mm margin of tissue to observe for the diagnostic
  • Organotypic cell cultures and mouse models to test the probing endoscope and its ability to perform the classification accurately

Main duties and responsibilities

  • Working and collaborating on the minimally invasive endoscope project
  • Analysis and publication of results
  • Participate in education, and PhD and master student supervision

Profile

  • PhD (or nearing completion of) in optics
  • Background in imaging and subsequent machine learning-assisted image analysis
  • Research experience with light shaping techniques and fluorescence detection
  • Publication record (relative to your career stage) in internationally leading journals
  • Independent and resourceful
  • Excellent written and oral communication skills in English
  • Team-spirited and ability to collaborate closely with project partners

We offer

  • A stimulating and international working environment
  • Competitive salary and excellent working conditions – more information can be found on our website (https://www.epfl.ch/campus/services/human-resources/en/basic-starting-salary-of-doctoral-assistants-and-postdocs/)
  • Opportunity to perform state-of-the-art research in one of the most dynamic scientific institutions in Europe.
  • Opportunity to interact with internationally renowned experts, and with a strong team of postdoctoral researchers and PhD students

Informations

​Only applications submitted through the online platform are considered. You are asked to supply:

  • A brief cover letter (pdf, up to 2 pages).

And in one PDF:

  • A CV with a publication list.
  • A research statement (pdf, up to 3 pages).
  • Contact details for 3 referees.

For any further information, please contact: victoria.fay@epfl.ch

Contract Start Date : As soon as possible
Activity Rate: 100%
Contract Type: CDD
Duration: 1 year, renewable
Reference : 1028










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